History

Year1907: Russian noble prize winner and father of modern immunology, Elie Metchnikoff, a scientist at the Pasteur institute, was the first conceptualize “probiotics”.

Year1953: The term "probiotics" was first introduced by Werner Kollath to describe organic and inorganic food supplements applied to restore health to patients suffering from manlnutrition. (Hamilton-Miller et al., 2003)

Year1965: Probiotic term was coined by Lilly and Stillwell. “Substances secreted by one organism which stimulate the growth of other’s”.

Year1971: “Organisms and substances which contribute to intestinal microbial balance.” (Spriti,1971)

Year1974: Parker defined the concept as, “Organisms and substances that have a beneficial effect on the host animal by contributing to its intestinal microbial balance”.

Year1989: “Live microbial supplements which beneficially affects the host animal by improving microbial balance." (Fuller,1989)

Year2001: “Live microorganisms which, when consumed in adequate amounts, confer a health benefit on the host”. (Food and Agricultural Organization / United Nations Organization / World Health Organization)